Isabel (Michelle Williams) has dedicated her life to working with the children in an orphanage in Calcutta. Theresa (Julianne Moore) is the multimillionaire head of a media company who lives with her artist husband (Billy Crudup) and their twin boys in New York. When word comes to Isabel of a mysterious and generous grant for the financially struggling orphanage, she must travel to New York to meet the benefactor Theresa in person.

Gallery, 15 Greene Street (btw Canal Street and Grand Street) Manhattan.

otsoNY Comments: 6-story cast-iron cooperative-apartment building completed in 1895. Designed by Samuel A. Warner as a warehouse, it is painted white, with cornices above the 1st, 2nd & 4th floors. The top floor has round-arched windows, and the building is capped by a simple dentiled roof cornice. The exposed south wall is clad in brown brick, with several seemingly random-placed windows. The ground floor is occupied by Foscarini lighting design. At the time of filming, this gallery belonged to Anita Rogers.

The Ludlow Hotel, 80 Ludlow Street (btw Stanton Street and E Houston Street) Manhattan.

Panna II Garden Indian Restaurant, 93 1st Avenue (btw East 5th and 6th Street) Manhattan.

otsoNY Comments: Christmas tree lights shine year-round inside this cash-only Indian restaurant.

Farmer's Market, Union Square West and East 16th Street, Manhattan.

26 Laight Street (btw Collister Street and Greenwich Street) Manhattan.

Collister Street (btw Laight Street and Hubert Street) Manhattan.