John (Brad Pitt) and Jane (Angelina Jolie) Smith are a normal married couple, living a normal life in a normal suburb and working normal jobs, too. However, in reality, John and Jane a re both skilled assassins working for different firms, both the best in their field, each concealing their true profession from the other. When both are assigned to kill a man named Benjamin Danz, nicknamed "The Tank", they encounter each other on the job and discover the truth. Both employers task one Smith to eliminate the other, and each must choose btw their personal and professional lives.