Ned (Paul Rudd) lived a happy life growing organic vegetables on a farm with his hippie girlfriend and his dog named Willie Nelson, but an unadvised incident with marijuana at a farmer's market lands him in jail. When he gets out of jail, he is off to live with his sisters. While Ned is still happy, his sisters are much less so after he manages to screw up one marriage, one job opportunity, one budding relationship and one domestic partnership. He sees those problems as breakdowns in communication, but his sisters see him as an idiot.

Liz's House, 542 1st Street (btw 8th Avenue and Prospect Park West) Brooklyn.

East 20th Street and Gramercy Park East, Manhattan.

West 55th Street and 9th Avenue, Manhattan.

Tasti D-lite Cafe, 1841 Broadway and West 60th Street, Manhattan.

Miranda's Apartment, 31 Jane Street and 8th Avenue, Manhattan.

Miranda's Workplace, Broadway and West 42nd Street, Manhattan.

26 New Dock Street, Brooklyn.