The turtles face a new challenge when Shredder escapes from custody and joins forces with Baxter Stockman, a mad scientist who plans to use a serum to take over the world. Along for the ride are Bebop and Rocksteady, two dimwitted henchmen who provide plenty of muscle. Luckily, the turtles have their own allies in April O'Neil (Megan Fox), Vernon Fenwick (Will Arnett) and Casey Jones (Stephen Amell), a hockey-masked vigilante. As the pizza-loving heroes prepare for battle, the notorious Krang also emerges to pose an even greater threat.

Madison Square Garden, 8th Avenue and West 33rd Street, Manhattan.

Grand Central Terminal, 89 East 42nd Street and Park Avenue, Manhattan.

Vazac's Horseshoe Bar, 108 East 7th Street and Avenue B, Manhattan.

TCRI HQ, 6th Avenue and 42nd Street, Manhattan.

East 42nd Street and 6th Avenue, Manhattan.

Cortlandt Alley (btw Walker Street and White Street) Manhattan.

Jane's Carousel, Brooklyn Bridge Park, Dock Street, Brooklyn.

185 West Broadway and Leonard Street, Manhattan.

Staple Street (btw Jay Street and Harrison Street) Manhattan.

Times Square (Broadway, 7th Avenue, West 42nd and 47th Streets) Manhattan.

Statue of Liberty, Liberty Island, New York Harbor.