Enduringly traumatized by the disappearance of her 3-year-old daughter 15 years ago, Julia Sandburg (Sigourney Weaver) has cut herself off from anyone once near and dear to her, including her husband Doug and her son Chris, who tried for years to penetrate her wall of isolation and despair, without success. But when Julia meets Louise (Kate Bosworth), a troubled young woman with a checkered past, all Julia's old psychic wounds painfully resurface, as does her illogical and increasingly irrational hope that Louise may be the daughter she lost so long ago.

otsoNY Comments: The cafe at 1414 on 6th Avenue was closed in 2012 and this unit along with its neighbours have been redeveloped. This building is now a hotel.

Sixth Avenue Cafe, 1414 6th Avenue and West 58th Street, Manhattan.

Windsor Pharmacy, 1402 6th Avenue and West 58th Street, Manhattan.

otsoNY Comments: Watch for this continuity error. When Julia's co-worker brings her a coffee to try out from his new coffee machine, he places it on her desk. The shot changes to him a few seconds later. When back to her, the coffee cup is turned 180 degrees - the handle is on the other side, the computer mouse is moved, and a stack of papers near her planner is moved. She did not move all of these things in those few seconds because she is holding some papers that she was reading when he walked into her office.

Julia's Workplace, 101 Park Avenue (btw East 40th Street and 41st Street) Manhattan.

The Mall, Central Park, Manhattan.

West 85th Street and Amsterdam Avenue, Manhattan.

Julia's Apartment, 160 West 85th Street and Amsterdam Avenue, Manhattan.

Port Authority Bus Terminal, 625 8th Avenue and West 42nd Street, Manhattan.