Out-of-work writer Eddie Morra's (Bradley Cooper) rejection by girlfriend Lindy (Abbie Cornish) confirms his belief that he has zero future. That all vanishes the day an old friend introduces Eddie to NZT, a designer pharmaceutical that makes him laser focused and more confident than any man alive. Now on an NZT-fueled odyssey, everything Eddie's read, heard or seen is instantly organized and available to him. As the former nobody rises to the top of the financial world, he draws the attention of business mogul Carl Van Loon (Robert De Niro), who sees this enhanced version of Eddie as the tool to make billions. But brutal side effects jeopardize his meteoric ascent. With a dwindling stash and hit men who will eliminate him to get the NZT, Eddie must stay wired long enough to elude capture and fulfill his destiny. If he can't, he will become just another victim who thought he'd found invincibility in a bottle.

Eddie's Apartment, 19 - 21 Henry Street and Catherine Street, Manhattan.

Broadway and West 28th Street, Manhattan.

Faust Harrison Pianos, 202 West 58th Street and 7th Avenue, Manhattan.

East 81st Street and 5th Avenue, Manhattan.

DeSalvio Playground, Mulberry Street and Spring Street, Manhattan.

Wollman Rink (btw East 62nd & 63rd Street) Central Park, Manhattan.

6th Avenue and West 48th Street, Manhattan.

Spring Street (btw Mulberry Street and Lafayette Street) Manhattan.

Brooklyn Bridge, Lower East Side, Manhattan.

Offices, 200 5th Avenue and Broadway, Manhattan.

East 17th Street and Union Square East, Manhattan.