New York advertising executive Roger Thornhill (Cary Grant) is kidnapped by a gang of spies led by Philip Vandamm (James Mason), who believe Thornhill is CIA agent George Kaplan. Thornhill escapes, but must find Kaplan in order to clear himself of a murder it is believed he committed. Following Kaplan to Chicago as a fugitive from justice, Thornhill is helped by beautiful Eve Kendall (Eva Marie Saint). In Chicago, she delivers a message to Kaplan that almost costs Thornhill his life when he is chased across a cornfield by a crop-dusting plane.

CIT Financial Office, 650 Madison Avenue (btw East 59th and 60th Streets) Manhattan.

The Plaza Hotel, 750 5th Avenue and Central Park South, Manhattan.

United Nations Headquarters, 1st Avenue (btw East 42nd and 48th streets) Manhattan.

Grand Central Terminal, 89 East 42nd Street and Park Avenue, Manhattan.