Henry Clark (Steve Martin) is a meticulous advertising executive from Ohio who runs his comfortable life by the numbers and by the book. Nancy Clark, a captivating romantic who wants to "suck the marrow out of life," will do anything it takes to create more passion in their marriage, even if her husband loses his mind in the process. What starts out as a predictable business trip turns into a riotous series of mishaps that weaves through Central Park, Greenwich Village, Times Square, the Fulton Fish Market and ultimately soars completely out of control when the overwhelmed couple arrive at a luxurious hotel. It is here they meet Mersault (John Cleese), an imperious, aristocratic hotel manager who becomes hilariously caught up in Nancy and Henry's mid-life crisis.

Susan Clark's Apartment, 148 2nd Avenue and East 9th Street, Manhattan.

West 4th Street and Charles Street, Manhattan.

Times Square (Broadway, 7th Avenue, West 42nd and 47th Streets) Manhattan.

Plaza Athénée Hotel, 37 East 64th Street and Park Avenue, Manhattan.   Hotel Plaza Athénée The Plaza Athénée is a hotel in Paris, France. It is located at 25 Avenue Montaigne, near the Champs Elysées and the Eiffel Tower. It is part of the Dorchester Collection group of international luxury hotels. Opened in 1911, the hotel has 145 rooms and 43 suites. Among the best-known of the latter are the Eiffel Penthouse Suite, with its stunning views of the tower, the city and the Seine; and the 437 m² (4,850-square foot) Royal Suite. To serve its guests, the hotel employs 520. There are several restaurants in the building. In 2000, Alain Ducasse chose the Athénée for his haute cuisine restaurant, named after himself. It serves dinner on weeknights and lunch on Thursdays and Fridays. Other eateries include the Relais Plaza (classical French cuisine), La Cour Jardin (Riviera-style cooking), La Galerie des Gobelins (breakfast, light lunch, tea and pastries) and Le Bar du Plaza, a popular night spot. Other amenities include a sauna and steam room. In 2008 the Dior Institut was added to the hotel. Famous guests who have stayed at the Athénée over the years include Mata Hari (who was arrested here), Josephine Baker, Rudolph Valentino, Grace Kelly, Gary Cooper, Jackie Kennedy, Mary Kate Olsen, Ashley Olsen, Matt Lauer, Katie Couric, Oprah Winfrey, Anna Wintour, Salma Hayek, and Penelope Cruz. Famous chefs to have worked there include Jacques Pépin. The hotel was featured in the final season of HBO's Sex and the City.

Park Avenue and East 64th Street, Manhattan.

Cherry Hill, Central Park, Manhattan.

Tavern on the Green, West 67th Street, Central Park, Manhattan.