Family living under one roof in New York must deal with a life-changing transformation by one that ultimately affects them all. Ray (Elle Fanning) is a teenager who has come to the realization that he isn't meant to be a girl and has decided to transition from female to male. His single mother, Maggie (Naomi Watts), must track down Ray's biological father to get his legal consent to allow Ray's transition. Dolly (Susan Sarandon), Ray's lesbian grandmother, is having a hard time accepting that she now has a grandson. They must each confront their own identities and learn to embrace change and their strength as a family in order to ultimately find acceptance and understanding.